Cardiovascular risk in the postnatal life of children born to women with systemic lupus erythematous




Darío Sandoval-Valdez, Research Unit, UNAM-INC, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City; Health Sciences Center, Universidad Autónoma de Aguascalientes, Aguascalientes. Mexico
Luis H. Silveira, Departament of Rheumatology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City. Mexico
Emma Rodríguez, Research Unit, UNAM-INC, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico


Systemic lupus erythematous (SLE) is an autoimmune disease with clinical manifestations in multiple organs, primarily striking women of reproductive age. Women with SLE can became pregnant such as any other healthy woman and carrier their pregnancy to term due to the improvement of health systems, but their specific inflammatory conditions could affect the microenvironment in which the fetus grows, and influence the development of placenta and the fetal heart. Until now, there is very little evidence of any increased risk of postnatal cardiovascular disease (CVD) in the apparently healthy children from women with SLE, but it is this great variability in the effects of lupus on pregnant products is related to.



Palabras clave: Systemic lupus erythematous. Maternal inflammation. Pregnancy. Offspring. Children. Cardiovascular disease. Heart.