Initial experience with cardiac contractility modulation devices in Latin America for the treatment of heart failure

Ulises Rojel-Martínez, Unidad de Arritmias y Marcapasos, Hospital General Dr. Eduardo Vázquez Navarro, Centro Médico del Sur, Puebla, Puebla, México
Carlos De-la-Fuente-Macip, Unidad de Arritmias y Marcapasos, Hospital General Dr. Eduardo Vázquez Navarro, Centro Médico del Sur, Puebla, Puebla, México
Arturo Enríquez-Silverio, Unidad de Arritmias y Marcapasos, Hospital General Dr. Eduardo Vázquez Navarro, Centro Médico del Sur, Puebla, Puebla, México
Karla I. Bozada-Nolasco, Unidad de Arritmias y Marcapasos, Hospital General Dr. Eduardo Vázquez Navarro, Centro Médico del Sur, Puebla, Puebla, México
Pablo A. Reátiga-Vega, Unidad de Arritmias y Marcapasos, Hospital General Dr. Eduardo Vázquez Navarro, Centro Médico del Sur, Puebla, Puebla, México
Flor M. Marquez-Maldonado, Unidad de Arritmias y Marcapasos, Hospital General Dr. Eduardo Vázquez Navarro, Centro Médico del Sur, Puebla, Puebla, México

Objective: To describe the initial experience of cardiac contractility modulation (CCM) implantation in Latin America. Method: We present the first two cases in Latin America of patients with heart failure with reduced left ventricular ejection fraction (LVEF) not candidates for cardiac resynchronization therapy in whom a CCM device was implanted. Results: In both patients we described improvement of the 6-minute walk test, functional class according to the NYHA and LVEF. Conclusions: The modulation of cardiac contractility is currently a treatment option for patients with heart failure in functional class III-IV, with LVEF 25-45%, and a QRS < 130 ms who are not candidates for cardiac resynchronization therapy.

Keywords: Heart failure. Electrical therapy. Modulation of cardiac contractility.