Validation of medical prescriptions’ suitability on patients with heart disease




Yoana Leyva-López, Pharmacy Department, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México
María de Lourdes Torres-Peláez, Pharmacy Department, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México
Angélica Guerrero-Barrera, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Xochimilco, Ciudad de México, México
Ingrid Padilla-Flores, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Xochimilco, Ciudad de México, México


Objective: Give pharmacotherapeutic following and study the variability and suitability of medical prescriptions given to patients during their hospitalization, through optimal and individualized pharmaceutical attention, that allows the best treatment stablished for each patient. Method: Data was captured prospectively, descriptively, and longitudinally with the purpose of analyzing the treatment’s suitability in patients with heart disease, through their pharmacotherapeutic following. Results: The pharmacotherapeutic evaluation of a population of 1,228 subjects proved that elderly male patients with multiple comorbidities and in polypharmacy are more susceptible of presenting severe drug interactions (65%) and prescription errors (14.4%). Conclusions: It is essential to have a specialized pharmacist within a multi-disciplinary medical team who manages the validation of each prescription’s suitability, making pharmaceutical interventions which allows the early detection of drug interactions and prescription errors, minimizing the probability of presenting real side effects and ensuring the effectiveness and security of the medical treatment.



Keywords: Drug interactions. Prescription errors. Comorbidities. Polypharmacy. Pharmacotherapeutic following.